Pathological aspects of lipid peroxidation (2010): Difference between revisions

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==Abstract==
<blockquote>Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the pathophysiology of ageing and classically oxidative stress-linked diseases, such as neurodegenerative diseases, diabetes and atherosclerosis (the main cause of cardiovascular complications). Striking evidences implicating LPO in foetal vascular dysfunction occurring in pre-eclampsia, in renal and liver diseases, as well as their role as cause and consequence to cancer development are addressed.</blockquote>
==Explanation==
==Explanation==
TBA
TBA  
==Highlights==
==Highlights==
TBA
TBA
==Related Studies==
==Related Studies==
TBA
TBA
==Official Abstract==
<blockquote>Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the pathophysiology of ageing and classically oxidative stress-linked diseases, such as neurodegenerative diseases, diabetes and atherosclerosis (the main cause of cardiovascular complications). Striking evidences implicating LPO in foetal vascular dysfunction occurring in pre-eclampsia, in renal and liver diseases, as well as their role as cause and consequence to cancer development are addressed.</blockquote>
==Publication Details==
==Publication Details==
===Authors===
===Authors===
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Negre-Salvayre A, Auge N, Ayala V, Basaga H, Boada J, Brenke R, Chapple S, Cohen G, Feher J, Grune T, Lengyel G, Mann GE, Pamplona R, Poli G, Portero-Otin M, Riahi Y, Salvayre R, Sasson S, Serrano J, Shamni O, Siems W, Siow RC, Wiswedel I, Zarkovic K, Zarkovic N. Pathological aspects of lipid peroxidation. Free Radic Res. 2010 Oct;44(10):1125-71. doi: 10.3109/10715762.2010.498478. PMID: 20836660.
Negre-Salvayre A, Auge N, Ayala V, Basaga H, Boada J, Brenke R, Chapple S, Cohen G, Feher J, Grune T, Lengyel G, Mann GE, Pamplona R, Poli G, Portero-Otin M, Riahi Y, Salvayre R, Sasson S, Serrano J, Shamni O, Siems W, Siow RC, Wiswedel I, Zarkovic K, Zarkovic N. Pathological aspects of lipid peroxidation. Free Radic Res. 2010 Oct;44(10):1125-71. doi: 10.3109/10715762.2010.498478. PMID: 20836660.
[[Category:Research Papers]]
[[Category:Research Papers]]
[[Category:Reviews]]
[[Category:Lipid peroxidation]]
[[Category:Lipid peroxidation]]

Latest revision as of 04:18, 24 March 2023

Abstract

Lipid peroxidation (LPO) product accumulation in human tissues is a major cause of tissular and cellular dysfunction that plays a major role in ageing and most age-related and oxidative stress-related diseases. The current evidence for the implication of LPO in pathological processes is discussed in this review. New data and literature review are provided evaluating the role of LPO in the pathophysiology of ageing and classically oxidative stress-linked diseases, such as neurodegenerative diseases, diabetes and atherosclerosis (the main cause of cardiovascular complications). Striking evidences implicating LPO in foetal vascular dysfunction occurring in pre-eclampsia, in renal and liver diseases, as well as their role as cause and consequence to cancer development are addressed.

Explanation

TBA

Highlights

TBA

Related Studies

TBA

Publication Details

Authors

Anne Negre-Salvayre, Nathalie Auge, Victoria Ayala, Huveyda Basaga, Jordi Boada, Rainer Brenke, Sarah Chapple, Guy Cohen, Janos Feher, Tilman Grune, Gabriella Lengyel, Giovanni E Mann, Reinald Pamplona, Giuseppe Poli, Manuel Portero-Otin, Yael Riahi, Robert Salvayre, Shlomo Sasson, Jose Serrano, Ofer Shamni, Werner Siems, Richard C M Siow, Ingrid Wiswedel, Kamelija Zarkovic, Neven Zarkovic

Journal

Free Radical Research

PubMed

https://pubmed.ncbi.nlm.nih.gov/20836660/

Full Text

https://www.tandfonline.com/doi/full/10.3109/10715762.2010.498478

Citation

Negre-Salvayre A, Auge N, Ayala V, Basaga H, Boada J, Brenke R, Chapple S, Cohen G, Feher J, Grune T, Lengyel G, Mann GE, Pamplona R, Poli G, Portero-Otin M, Riahi Y, Salvayre R, Sasson S, Serrano J, Shamni O, Siems W, Siow RC, Wiswedel I, Zarkovic K, Zarkovic N. Pathological aspects of lipid peroxidation. Free Radic Res. 2010 Oct;44(10):1125-71. doi: 10.3109/10715762.2010.498478. PMID: 20836660.